The objective of this project is to compare the stiffness of periprosthetic fracture fixation using one locked plate versus two orthogonal locked plates. This is a laboratory study using synthetic composite femurs with simulated, comminuted Vancouver B1 periprosthetic fracture at the distal tip of an intact cement prosthesis. Fixation was achieved first with one locking plate with unicortical screws and cables, proximally. Construct stiffness was measured before and after load cycling in physiologic orientation. Axial load, torsional strength, and resistance to three-point bending were determined by fracture site displacement. Additional anterior plating to the eight specimens was followed by repeat loading experiments. Results from this mechanical study will provide insight into providing the stiffer fixation for a complex type of periprosthetic fracture.