Dr. Nercessian is a 1981 graduate of the College of Physicians and Surgeons of Columbia University. He completed his general surgery training at the Barnes Hospital at Washington University in St. Louis and Orthopaedic training at the New York Orthopaedic Hospital, Columbia Presbyterian Medical Center. He then completed a fellowship in hip and knee surgery with Dr. Stinchfield at the New York Orthopaedic Hospital, Columbia Presbyterian Medical Center. He spent a year as a training fellow at Massachusetts General Hospital, the Mayo Clinic, Hospital for Special Surgery and other major institutions in the United States and Europe.

He is active in caring for patients with hip and knee problems including trauma. He is the author of more than 60 scientific articles and has been a visiting professor at many national and international medical institutions. Dr. Nercessian is also a member of many national scientific organizations including the American College of Surgeons. As a Board Certified Orthopaedic surgeon, Dr. Nercessian's particular areas of research interest are hip and knee surgery including the use of allograft in complex revision operations and in failed hip and knee surgery with significant bone loss. Other areas of research include identifying factors that contribute to post operative complications following total hip arthroplasty.